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Found 17 of ic50 data for polymerid = 9827,50006168
TargetHTH-type transcriptional regulator EthR(Mycobacterium tuberculosis)
Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50363052(CHEMBL1946956)
Affinity DataIC50:  400nMAssay Description:Inhibition of Mycobacterium tuberculosis H37Rv EthRMore data for this Ligand-Target Pair
TargetHTH-type transcriptional regulator EthR(Mycobacterium tuberculosis)
Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50363052(CHEMBL1946956)
Affinity DataIC50:  400nMAssay Description:Inhibition of EthR binding to ethA promoter in 106-bp biotinylated DNA preincubated for 5 mins measured for 3 mins by surface plasmon resonance assayMore data for this Ligand-Target Pair
TargetHTH-type transcriptional regulator EthR(Mycobacterium tuberculosis)
Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50343344(1-(thiophen-2-ylacetyl)-4-(3-thiophen-2-yl-1,2,4-o...)
Affinity DataIC50:  500nMAssay Description:Inhibition of Mycobacterium tuberculosis EthR interaction to ethA promoter after 5 mins by surface plasmon resonance assayMore data for this Ligand-Target Pair
TargetHTH-type transcriptional regulator EthR(Mycobacterium tuberculosis)
Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50462583(CHEMBL1234901)
Affinity DataIC50:  580nMAssay Description:Inhibition of Mycobacterium tuberculosis EthRMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetHTH-type transcriptional regulator EthR(Mycobacterium tuberculosis)
Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50343346(4-Methyl-1-[4-(3-thiophen-2-yl-1,2,4-oxadiazol-5-y...)
Affinity DataIC50:  900nMAssay Description:Inhibition of Mycobacterium tuberculosis EthR interaction to ethA promoter after 5 mins by surface plasmon resonance assayMore data for this Ligand-Target Pair
TargetHTH-type transcriptional regulator EthR(Mycobacterium tuberculosis)
Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50363017(CHEMBL1945812)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of EthR binding to ethA promoter in 106-bp biotinylated DNA preincubated for 5 mins measured for 3 mins by surface plasmon resonance assayMore data for this Ligand-Target Pair
TargetHTH-type transcriptional regulator EthR(Mycobacterium tuberculosis)
Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50343347(2-Cyclopropyl-1-[4-(3-thiophen-2-yl-[1,2,4]oxadiaz...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis EthR interaction to ethA promoter after 5 mins by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHTH-type transcriptional regulator EthR(Mycobacterium tuberculosis)
Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50343348(2-Cyclopentyl-1-[4-(3-thiophen-2-yl-[1,2,4]oxadiaz...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis EthR interaction to ethA promoter after 5 mins by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHTH-type transcriptional regulator EthR(Mycobacterium tuberculosis)
Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50343350(4,4,4-trifluoro-1-(4-(3-(thiophen-2-yl)-1,2,4-oxad...)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of EthR binding to ethA promoter in 106-bp biotinylated DNA preincubated for 5 mins measured for 3 mins by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHTH-type transcriptional regulator EthR(Mycobacterium tuberculosis)
Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50343350(4,4,4-trifluoro-1-(4-(3-(thiophen-2-yl)-1,2,4-oxad...)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis EthR interaction to ethA promoter after 5 mins by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHTH-type transcriptional regulator EthR(Mycobacterium tuberculosis)
Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50343351(4,4,4-Trifluoro-1-[(R)-3-(3-thiophen-2-yl-1,2,4-ox...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis EthR interaction to ethA promoter after 5 mins by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHTH-type transcriptional regulator EthR(Mycobacterium tuberculosis)
Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50343351(4,4,4-Trifluoro-1-[(R)-3-(3-thiophen-2-yl-1,2,4-ox...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of EthR binding to ethA promoter in 106-bp biotinylated DNA preincubated for 5 mins measured for 3 mins by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHTH-type transcriptional regulator EthR(Mycobacterium tuberculosis)
Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50363015(CHEMBL1945701)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of EthR binding to ethA promoter in 106-bp biotinylated DNA preincubated for 5 mins measured for 3 mins by surface plasmon resonance assayMore data for this Ligand-Target Pair
TargetHTH-type transcriptional regulator EthR(Mycobacterium smegmatis (strain ATCC 700084 / mc(2...)
University Of Lille

Curated by ChEMBL
LigandPNGBDBM50395186(CHEMBL1612418)
Affinity DataIC50:  2.90E+3nMAssay Description:Inhibition at EthR in Mycobacterium smegmatis mc2 155 assessed as reactivation of beta-glucuronidase activity measured over 48 hrs by Spectrophotomet...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHTH-type transcriptional regulator EthR(Mycobacterium tuberculosis)
Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50343349(2-Cyclohexyl-1-[4-(3-thiophen-2-yl-[1,2,4]oxadiazo...)
Affinity DataIC50:  3.50E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis EthR interaction to ethA promoter after 5 mins by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHTH-type transcriptional regulator EthR(Mycobacterium tuberculosis)
Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50343345(2-Phenyl-1-[4-(3-thiophen-2-yl-[1,2,4]oxadiazol-5-...)
Affinity DataIC50:  5.60E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis EthR interaction to ethA promoter after 5 mins by surface plasmon resonance assayMore data for this Ligand-Target Pair
TargetHTH-type transcriptional regulator EthR(Mycobacterium tuberculosis)
Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50363018(CHEMBL1945813)
Affinity DataIC50:  9.10E+3nMAssay Description:Inhibition of EthR binding to ethA promoter in 106-bp biotinylated DNA preincubated for 5 mins measured for 3 mins by surface plasmon resonance assayMore data for this Ligand-Target Pair